Name | Thonningianin A |
Synonyms | Thonningianin A thonningianin A Pinocembrin dihydrochalcone 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-beta-D-glucoside 1-Propanone, 1-[4-[[4,6-O-[[(1S)-4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-diyl]dicarbonyl]-3-O-(3,4,5-trihydroxybenzoyl)-β-D-glucopyranosyl]oxy]-2,6-dihydroxyphenyl]-3-phenyl- |
CAS | 271579-11-4 |
Molecular Formula | C42H34O21 |
Molar Mass | 874.71 |
Density | 1.89±0.1 g/cm3(Predicted) |
Boling Point | 1364.1±65.0 °C(Predicted) |
Specific Rotation(α) | -141 (c, 0.1 in MeOH) |
Solubility | Insuluble (5.5E-4 g/L) (25 °C) |
Appearance | Powder |
pKa | 6.80±0.40(Predicted) |
Storage Condition | 2-8℃ |
MDL | MFCD30725006 |
In vitro study | Thonningianin A effectively inhibited the proliferation of HepG-2 cells by inducing apoptosis, as evidenced by increase in the sub-G1 cell population, DNA fragmentation, and increase in the content of reactive oxygen species. |
biological activity | Thonningianin A is A tanned flower, isolated from A methanol extract of the African herb tongningning. The antioxidant properties of Thonningianin A include free radical scavenging, resistance to superoxide generation and metal chelation. Has anti-cancer activity. |